How to take the medication

Managing your medicine and routine

You should take osimertinib once a day. Your doctor, nurse or pharmacist will tell you how many tablets to take. Do not chew, break or crush the tablets.¹

Osimertinib is taken by mouth. Swallow the tablet whole with water. Take Osimertinib every day at the same time.^1,2

You can take this medicine with or without food.^1,2

Osimertinib may fit into your daily routine and can be taken at home or on-the-go^1-3

Keep them in the original package and at room temperature, away from heat and direct sunlight

Keep them safe and out of sight and reach of children

If your treatment is stopped return any unused tablets to the pharmacist

It is important to get a new prescription before you run out of tablets and make sure you have plenty for holidays

What if I miss a dose?

If you forget a dose, take it as soon as you remember it. However, if it is less than 12 hours until your next dose is due, skip the missed dose. Take your next normal dose at its scheduled time.²

Your doctor may change your dose, temporarily stop, or permanently stop treatment with osimertinib if you experience side effects.³

It’s important to follow your doctor’s guidance for staying on track with your treatment.

What if I can’t swallow osimertinib whole?

Put the tablet in a glass. Add 50 mL (about two-thirds of a tumblerful) of still (non-fizzy) water – do not use any other liquids.²

Stir the water until the tablet breaks up into very small pieces - the tablet will not completely dissolve.^2,3

Drink the liquid straight away.²

To make sure you have taken all of the medicine, rinse the glass thoroughly with another 50 mL of water and drink it.²

Potential
side effects

Like all medicines, you may experience side effects on osimertinib

Learn more

References:

Tagrisso 40 mg and 80 mg film coated tablets. Summary of product characteristics.
Tagrisso 40 mg and 80 mg film coated tablets. Patient Information Leaflet.
Medlineplus. Osimertinib. Available at: https://medlineplus.gov/druginfo/meds/a616005.html. Accessed December 2023.

GB-73012 I DOP: January 2026

This website is only intended for UK patients who have been prescribed TAGRISSO^® (osimertinib), which is indicated after surgery in adults with stage 1B-3A NSCLC with a particular EGFR mutation, and also in locally advanced or metastatic NSCLC with a particular EGFR mutation. It does not replace the Patient Information Leaflet, which you can find in the carton containing your medicine and which you should read alongside this information. If you have any questions about your treatment, talk to your healthcare team or refer to the Patient Information Leaflet.

Reporting side effects

If you get any side effects, talk to your doctor, nurse or pharmacist. This includes any possible side effects not listed in the Patient Information Leaflet. You can also report side effects directly via the Yellow Card Scheme, website: https://yellowcard.mhra.gov.uk. By reporting side effects you can help provide more information on the safety of medicines.

Side effects can also be reported to AstraZeneca in the following ways:

Online: https://contactazmedical.astrazeneca.com

Email: Medical.InformationUK@astrazeneca.com

No imagery of real patients has been used on this site.

Welcome to tagrissoandme.co.uk*

How to take the medication

What if I miss a dose?

It’s important to follow your doctor’s guidance for staying on track with your treatment.

What if I can’t swallow osimertinib whole?

Potentialside effects

Potential
side effects